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The word epitope was coined by Niels Kaj Jerne in 1960. He defined the term as: "surface configurations, single determinants, structural themes, immunogenic elements, haptenic groups, antigenic patterns, specific areas" (Aalberse RC, Crameri R. "IgE‐binding epitopes: a reappraisal". Allergy 2011; 66: 1261–1274.) It is the place on the surface of ...


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