My intuition suggests different word orders with and without the enclitic -ne. For example:
Vir canit. — The man sings.
Canitne vir? — Does the man sing?
I know full well that Latin word order is fairly free, but nevertheless there are tendencies. This question is about those tendencies, as I expect there to be no hard rules. Putting the predicate at the end of the direct statement is common, and I will not contest that here. However, I am not sure what effect adding -ne to the predicate should have on word order.
My intuition suggests putting the predicate first when it comes with -ne. Is this actually the case in classical Latin? Does -ne have any observable effect on word order? For example, are the typical positions of est and estne different?